Hypoxis hemerocallidea is one of Southern Africa’s most important and popular medicinal plants. It is used for a wide a range of traditional. Background. Hypoxis hemerocallidea is a native plant that grows in the Southern African regions and is well known for its beneficial medicinal effects in the. Phytother Res. Feb;23(2) doi: /ptr ‘African potato’ ( Hypoxis hemerocallidea corm): a plant-medicine for modern and 21st century.

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Standard meals were provided until 24 hours after dosing, and the times at which meals were started and finished were recorded as well as the amounts consumed. Pre-study medical screening was performed within a month of initiating the study, and volunteers who passed the physical, medical and laboratory screening tests were enrolled.

In the present study, there were significant decreases in the serum levels of total protein and albumin in groups 2, 3, and 4 when compared to the normal control and group 5.

The washout period between the administration of the efavirenz doses was 28 days. Table 4 Effects of H. GSH is another important endogenous antioxidant and a cofactor of some enzymes taking part in the reduction of ROS; hence it has been regarded as a marker of free radical damage [ 26 ].

Hypoxis hemerocallidea | Plantz Africa

Laboratory tests for all volunteers were normal; no serious adverse effects were reported or noted during the study. Drug interactions in African herbal remedies. South African Journal hyypoxis Science. Other species in the genus are also toxic to humans H.


North American Journal of Medical Sciences. Table 3 Effects of H. Fire promotes the growth of new leaves.

Hypoxis hemerocallidea

In this present study, significant elevation in the fasting blood glucose levels up to the diabetic range groups 2, 3, and 4 was observed 48 hours after STZ-induced diabetes. Ferric reducing antioxidant power of tissue samples was assessed using the method that was developed by Benzi and Strain in The hypoxidaceae super family is made up of 8 genera and species [ 17 ].

National Antiretroviral Treatment Guidelines.

Blood pressure, pulse and body temperature were taken before and 4 hours after dosing with efavirenz. This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. This family consists of several types of species which include H.

Hypoxis hemerocallidea – Wikipedia

Effects of Hypoxis hemerocallidea Fisch. Hence, co-administration of AP with efavirenz did not appear to affect the pharmacokinetics of efavirenz. Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats.

In a study on the plants sold at muti markets in the Eastern Cape, Hypoxis hemerocallidea was the most-traded plant. Possible effects of co-administration of NHPs and ARVs include increased side-effects of ARVs and losing the control of viral replication, which could lead to non-compliance and therapeutic failure, respectively.

The potential of South African plants in the development of new medicinal products.


J Pharmacol Exp Ther ; This study investigated the effects of Hypoxis hemerocallidea in the kidney and liver tissue of STZ-induced diabetic male Wistar rats by assessing the antioxidant activities and selected biomarkers. Preparation and analysis of AP. It basically cut the bottom piece of the corm off just above the roots.

Support Center Support Center. To the best of our knowledge, this is the first time a study would focus mainly on the antioxidant activities as well as their potential deleterious effects using animal model. Is this really the best The lower surface of the leaves is densely hairy with white hairs. Services on Demand Article. It has also been predicted that million people will be diabetics by and currently; million people are diabetics [ 78 ].

Elevated relative liver weights were observed in groups 2 and 3 compared to the normal control group 2 and group 5. Suitability of Acacia xanthophloea for dry climates Differential modulation of P-glycoprotein expression and activity by non-nucleoside HIV-1 reverse transcriptase inhibitors in cell culture. In the kidney tissue, CAT activity in the diabetic control was increased significantly when compared to groups 1, 4, and 5.

The animal feeding was conducted over a period of 6 weeks. The tuberous part of the H. African Journal of Biotechnology.